This randomized clinical trial investigates if prehospital pulse-dose glucocorticoid treatment has a cardioprotective effect in patients with ST-segment elevation myocardial infarction (STEMI).
This post hoc analysis of the PARADIGM-HF and PARAGON-HF randomized clinical trials assesses the effects of sacubitril/valsartan on all-cause hospitalizations across the spectrum of left ventricular ejection fraction.
This cohort study estimates the UK population prevalence of disease-causing transthyretin gene variants and evaluates associated cardiac phenotypes and outcomes.
This cohort study analyzes data for 560 patients newly diagnosed with systemic AL amyloidosis to assess the differences between biomarkers, echocardiography, and cardiovascular magnetic resonance with extracellular volume mapping in characterizing cardiac amyloid infiltration.
This Viewpoint highlights the limited representation of patients with non-English language preference (NELP) in cardiology clinical trials and registries and recommends several methods to better include patients with NELP.
A woman in her mid-20s presented with acute fever, chest pain, and exertional dyspnea. Electrocardiogram results showed sinus tachycardia, QRS widening, low-voltage complexes, and ST-segment elevation. What would you do next?
This randomized clinical trial investigates the effects of verinurad on exercise capacity and symptoms in patients with heart failure with preserved ejection fraction (HFpEF) and elevated serum uric acid levels.
This randomized clinical trial evaluates the safety and efficacy of administration of protamine to reduce bleeding following transcatheter aortic valve implantation vs placebo, selective protamine administration.
This randomized clinical trial investigates the optimal antithrombic therapy after percutaneous left atrial appendage occlusion (LAAO).
This secondary analysis of the Valsartan in Acute Myocardial Infarction (VALIANT) and Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI (PARADISE-MI) randomized clinical trials investigates the changes over time in sudden death rate after myocardial infarction and the characteristics of people dying suddenly.
This survey study of women who were pregnant during cardiology fellowship assesses health and safety measures implemented during pregnancy.
This case report discusses progressive cardiogenic shock in a man aged 78 years after catheter ablation for ventricular tachycardia.