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Day

August 26, 2024
Original Investigation

Endovascular vs Medical Management of Acute Basilar Artery Occlusion: A Secondary Analysis of a Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. Published online August 26, 2024. doi:10.1001/jamaneurol.2024.2652

This secondary analysis of a randomized clinical trial assesses 1-year clinical outcomes following endovascular thrombectomy in patients with acute basilar artery occlusion.

Research Letter

Association of Cardiovascular Events With Spouse’s Subsequent Dementia

Abstract Full Text
JAMA Neurol. Published online August 26, 2024. doi:10.1001/jamaneurol.2024.2612

This cohort study evaluates whether a spousal cardiovascular event is associated with one’s own risk of dementia.

August 19, 2024
Viewpoint

Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases

Abstract Full Text
JAMA Neurol. Published online August 19, 2024. doi:10.1001/jamaneurol.2024.2464

This Viewpoint describes the evidence for iatrogenic disease based on amyloid-β prions and the possibility that Alzheimer disease has an iatrogenic form wherein amyloid β and tau behave as prions that transmit the disease.

Editorial

JAMA Neurology Editorial Fellowship—Call for Applicants

Abstract Full Text
JAMA Neurol. Published online August 19, 2024. doi:10.1001/jamaneurol.2024.2554
Original Investigation

Localized Nicardipine Release Implants for Prevention of Vasospasm After Aneurysmal Subarachnoid Hemorrhage: A Randomized Clinical Trial

Abstract Full Text
open access has audio
JAMA Neurol. Published online August 19, 2024. doi:10.1001/jamaneurol.2024.2564

This randomized clinical trial investigated the safety and efficacy of nicardipine release implants for preventing proximal angiographic vasospasm after aneurysmal subarachnoid hemorrhage.

Lecanemab and Vascular-Amyloid Deposition in Brains of People With Down Syndrome

Abstract Full Text
JAMA Neurol. Published online August 19, 2024. doi:10.1001/jamaneurol.2024.2579

This study investigates the binding properties of lecanemab in the brains of people with Down syndrome, in anticipation of their inclusion in clinical trials or access to antiamyloid immunotherapies.

Comment & Response

Sex Differences in Case-Fatality Rates of Stroke

Abstract Full Text
JAMA Neurol. Published online August 19, 2024. doi:10.1001/jamaneurol.2024.2596

Sex Differences in Case-Fatality Rates of Stroke—Reply

Abstract Full Text
JAMA Neurol. Published online August 19, 2024. doi:10.1001/jamaneurol.2024.2599
August 12, 2024
Viewpoint

It Is Time for Medicare to Cover Driving Safety Assessments

Abstract Full Text
JAMA Neurol. Published online August 12, 2024. doi:10.1001/jamaneurol.2024.2461

This Viewpoint advocates for Medicare coverage of driving assessments for older individuals.

Review

Endovascular Stroke Thrombectomy for Patients With Large Ischemic Core: A Review

Abstract Full Text
has active quiz
JAMA Neurol. Published online August 12, 2024. doi:10.1001/jamaneurol.2024.2500

This narrative review discusses the results of 6 recently published trials on the efficacy and safety of endovascular thrombectomy as treatment for patients with ischemic stroke, anterior-circulation large vessel occlusions, and large areas of ischemic change and highlights areas of persistent uncertainty in the use of this treatment.

Images in Neurology

Parkinsonism Following Chimeric Antigen Receptor T Cell Therapy

Abstract Full Text
has active quiz
JAMA Neurol. Published online August 12, 2024. doi:10.1001/jamaneurol.2024.2506

This case report describes a 67-year-old woman who had received adoptive immunotherapy with chimeric antigen receptor T cells for multiple myeloma and was experiencing parkinsonism-like symptoms.

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